Cefrin powder

Dexa Medica

Ingredients in every vial

Cefpirome 1 g

Each package contains

1 vial of 1 g

Other details

Dosage form:Powder for Injection
Flavour: None

W.H.O. classification

ATC Level 1: J - Antiinfectives for systemic use
ATC Level 2: J01 - Antibacterials for Systemic Use
ATC Level 3: J01D - Other Beta-Lactam Antibacterials in ATC

Warnings

Pregnancy

NOT SAFEThis item is not safe for use during pregnancy.

Lactation

NOT SAFEThis item is not safe for use during lactation.

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

CONSULT YOUR DOCTORSafety of this item for use while operating heavy machinery has not been established. Please consult your doctor.

Available in

Indonesia
The Philippines

Dosage information

0 TO 12 YEARS OLD
Adequate clinical data for children <12 years of age is insufficient. Therefore, cefpirome should not be used for this age group 18 YEARS OLD AND ABOVE
The following dosages are recommended for moderate to severe infections in patients with normal renal function:

Complicated upper and lower urinary tract infections
– Unit dose: 1 g
– Dosage intervals: 12 hours
– Total daily dose: 2 g

Skin and soft tissue infections
– Unit dose: 1 g
– Dosage intervals: 12 hours
– Total daily dose: 2 g

Lower respiratory tract infections
– Unit dose: 1 to 2 g
– Dosage intervals: 12 hours
– Total daily dose: 2 to 4g

Bacteremia/septicemia
– Unit dose: 2 g
– Dosage intervals: 12 hours
– Total daily dose: 4g

Infections in neutropenic patients
– Unit dose: 2 g
– Dosage intervals: 12 hours
– Total daily dose: 4g

Severe infections
– Unit dose: 2 g
– Dosage intervals: 12 hours
– Total daily dose: 4g

65 YEARS OLD AND ABOVE
No adjustment is required unless renal impairment is present.

PATIENTS WITH IMPAIRED RENAL FUNCTION
Cefpirome is excreted principally by the kidney. The dose must therefore be reduced in patients with impaired renal function to compensate for the slower excretion.

CrCl 20-50 ml/minute:
Initial dose 1 g, maintenance dose 0.5 g twice daily
Initial dose 2 g, maintenance dose 1 g twice daily

CrCl 5-20 ml/minute:
Initial dose 1 g, maintenance dose 0.5 g once daily
Initial dose 2 g, maintenance dose 1 g once daily

CrCl ˂5 ml/minute
Initial dose 1 g, maintenance dose 0.5 g once daily ± 0.25 g
Initial dose 2 g, maintenance dose 1 g once daily ± 0.5 g

Hemodialysis patients
Initial dose 1 g, maintenance dose immediately after dialysis
Initial dose 2 g, maintenance dose 1 g once daily
immediately after dialysis

Indication

For infection treatment, whether before the causative organism is known or infections caused by bacterial organisms sensitive to cefpirome.
– Lower respiratory tract infections (bronchopneumonia, lobar pneumonia)
– Complicated upper (pyelonephritis) and lower urinary tract infections
– Skin and soft tissue infections (cellulitis, skin abscess and infected wound)
– Infections in neutropenic patients
– Bacteremia/septicemia
– Severe infections

Disclaimer

The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for informational purposes only. This tool may not cover all possible drug interactions or all warnings or alerts. Please check with a physician if you have health questions or concerns about interactions or go to the appropriate government authority for a comprehensive list of medical warnings. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

All of the content present on this website, including written text, photographs, videos, graphics, and other resources we might include (these will fall under the collective term of “website”), is meant to educate and should not be perceived as a substitution for professional medical advice, diagnosis or treatment. You should not resort to the website information to arrive at a diagnosis or treatment solution for your health problems or various medical conditions. It does not replace medical care, provided by a medical specialist. In the situation, you have specific symptoms and you might suspect that you are suffering from a medical problem, it is for the best to consult your physician.