Fluorourasil 500mg / 10ml injection

Ferron Par Pharmaceuticals

Ingredients in every 10 ml

Fluorouracil 500 mg

Each package contains

1 vial of 10 ml

Other details

Dosage form:Injection
Flavour: None

W.H.O. classification

ATC Level 1: L - Antineoplastic and immunomodulating agents
ATC Level 2: L01 - Antineoplastic Agents
ATC Level 3: L01B - Antimetabolites



NOT SAFEThis item is not safe for use during pregnancy.


NOT SAFEThis item is not safe for use during lactation.


CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.


CAUTIONThis item may not be safe for use while operating heavy machinery. Use with caution.

Available in


Dosage information

Usual dosage
12 mg/kg i.v once daily for 4 successive days. The maximum daily dose of fluorouracil is 800 mg. If no toxicity is observed, 6 mg/kg are given on days 6, 8, 10 and 12 (no therapy is given on days 5, 7, 9 and 11).Therapy is discontinued at the end of day 12, even if no toxicity is observed.

Poor risk patients or those with inadequate nutritional state.
6 mg/kg/day for 3 days. If no toxicity is observed, 3 mg/kg are given on day 5, 7 and 9 (no therapy on day 4, 6 and 8). The maximum daily dose is 400 mg. The above sequence of injections constitutes a course of therapy.

Maintenance therapy
When toxicity has not been a problem, it is recommended to continue therapy using either of the following schedules:
– Repeat dosage of first course every 30 days after the last day of the previous course of treatment.
– When toxic signs resulting from the initial course of therapy have subsided, administer a maintenance dosage of 10 to 15 mg/kg/week as a single dose. Do not exceed 1 g per week.
The amount of the drug to be used may vary from 9 to 45 courses of treatment during periods which ranged from 12 to 60 months.

Fluorouracil injection is for i.v use only and no dilution is required. Actual body weight is used for dosage calculation, except in obese patients and in the presence of abnormal fluid retention (edema, ascites), the estimated ideal body weight is used.


For palliative treatment of carcinoma of the colon, rectum, breast, stomach and pancreas in patients who are considered incurable by surgery or other means.


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