Fluorourasil 500mg / 10ml injection
Ingredients in every 10 ml
Each package contains
|ATC Level 1:||L - Antineoplastic and immunomodulating agents|
|ATC Level 2:||L01 - Antineoplastic Agents|
|ATC Level 3:||L01B - Antimetabolites|
18 YEARS OLD AND ABOVE
12 mg/kg i.v once daily for 4 successive days. The maximum daily dose of fluorouracil is 800 mg. If no toxicity is observed, 6 mg/kg are given on days 6, 8, 10 and 12 (no therapy is given on days 5, 7, 9 and 11).Therapy is discontinued at the end of day 12, even if no toxicity is observed.
Poor risk patients or those with inadequate nutritional state.
6 mg/kg/day for 3 days. If no toxicity is observed, 3 mg/kg are given on day 5, 7 and 9 (no therapy on day 4, 6 and 8). The maximum daily dose is 400 mg. The above sequence of injections constitutes a course of therapy.
When toxicity has not been a problem, it is recommended to continue therapy using either of the following schedules:
– Repeat dosage of first course every 30 days after the last day of the previous course of treatment.
– When toxic signs resulting from the initial course of therapy have subsided, administer a maintenance dosage of 10 to 15 mg/kg/week as a single dose. Do not exceed 1 g per week.
The amount of the drug to be used may vary from 9 to 45 courses of treatment during periods which ranged from 12 to 60 months.
Fluorouracil injection is for i.v use only and no dilution is required. Actual body weight is used for dosage calculation, except in obese patients and in the presence of abnormal fluid retention (edema, ascites), the estimated ideal body weight is used.
For palliative treatment of carcinoma of the colon, rectum, breast, stomach and pancreas in patients who are considered incurable by surgery or other means.
All of the content present on this website, including written text, photographs, videos, graphics, and other resources we might include (these will fall under the collective term of “website”), is meant to educate and should not be perceived as a substitution for professional medical advice, diagnosis or treatment. You should not resort to the website information to arrive at a diagnosis or treatment solution for your health problems or various medical conditions. It does not replace medical care, provided by a medical specialist. In the situation, you have specific symptoms and you might suspect that you are suffering from a medical problem, it is for the best to consult your physician.